(2-Methylpyrimidin-5-yl)methanol → 2-(2-Methylpyrimidin-5-yl)acetonitrile

HRID 512138

Reaction equation

HRID 512138 reaction equation
FC(F)(F)[C:3]1[N:8]=[CH:7][C:6]([CH2:9][C:10]#[N:11])=[CH:5][CH:4]=1.CC1N=CC(CO)=C[N:16]=1>>[CH3:4][C:3]1[N:16]=[CH:5][C:6]([CH2:9][C:10]#[N:11])=[CH:7][N:8]=1

Participants

3

Reactant 2

HCID 14686706(2-Methylpyrimidin-5-yl)methanolHCID 508511273-Pyridineacetonitrile, 6-(trifluoromethyl)-

Product 1

HCID 847623642-(2-Methylpyrimidin-5-yl)acetonitrile

Procedure

(2-Methyl-pyrimidin-5-yl)-acetonitrile was prepared as described above for the synthesis of (6-trifluoromethyl-pyridin-3-yl)-acetonitrile starting from (2-methyl-pyrimidin-5-yl)-methanol

Sources & evidence

ORD record
ord-bf4f238451c44d24b1972ecc7f567a89
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Linked notes

Loading…