2-Chloro-3-(trifluoromethyl)benzoic acid → HCID 86716441, compound

HRID 512384

Reaction equation

HRID 512384 reaction equation
[Cl:1][C:2]1[C:10]([C:11]([F:14])([F:13])[F:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:15][C:16]1([F:34])[CH2:21][CH2:20][C:19]([CH2:32][NH2:33])([C:22]2[CH:23]=[N:24][C:25]([C:28]([F:31])([F:30])[F:29])=[N:26][CH:27]=2)[CH2:18][CH2:17]1>>[Cl:1][C:2]1[C:10]([C:11]([F:14])([F:13])[F:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:33][CH2:32][C:19]1([C:22]2[CH:23]=[N:24][C:25]([C:28]([F:31])([F:30])[F:29])=[N:26][CH:27]=2)[CH2:20][CH2:21][C:16]([F:15])([F:34])[CH2:17][CH2:18]1)=[O:6]

Participants

3

Reactant 2

HCID 27366772-Chloro-3-(trifluoromethyl)benzoic acidHCID 86716351HCID 86716351, compound

Product 1

HCID 86716441HCID 86716441, compound

Procedure

From 2-chloro-3-trifluoromethylbenzoic acid and [4,4-Difluoro-1-(2-(trifluoromethyl)pyrimidin-5-yl)cyclohexyl]methanamine. LCMS (MH+): m/z=502.1, tR (minutes, Method F)=3.25

Sources & evidence

ORD record
ord-b3248e2e105b4cf28de40cf65e043d74
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Linked notes

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