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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 51242Generated: October 25, 2026

(2,3-Dimethoxyphenyl)(4-pyridinyl)methanol → (2,3-Dimethoxyphenyl)(piperidin-4-yl)methanol

https://huagongshe.com/reaction/51242

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2,3-Dimethoxyphenyl)(4-pyridinyl)methanolHCID 314742—
SolventPyridineHCID 1049—
Product(2,3-Dimethoxyphenyl)(piperidin-4-yl)methanolHCID 10890362—

Reaction Steps

In Scheme F, step e, the pyridine functionality of 4-[1-hydroxy-1-(2,3-dimethoxyphenyl)methyl]pyridine (10) is reduced to give 4-[1-hydroxy-1-(2,3-dimethoxyphenyl)methyl]piperidine (11).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06713627B2
Source datasetuspto-grants-2004_03
ORD IDord-6e2be86b12ec4277b90a316b046a151a
Source noteuspto-grants-2004_03