Veratrole → 4-(2,3-Dimethoxybenzoyl)pyridine

HRID 51245

Reaction equation

COCN[C:5]([C:7]1[CH:12]=[CH:11][N:10]=[CH:9][CH:8]=1)=[O:6].[C:13]1([O:21][CH3:22])[C:14](=[CH:17][CH:18]=[CH:19][CH:20]=1)[O:15][CH3:16]>>[CH3:16][O:15][C:14]1[C:13]([O:21][CH3:22])=[CH:20][CH:19]=[CH:18][C:17]=1[C:5]([C:7]1[CH:8]=[CH:9][N:10]=[CH:11][CH:12]=1)=[O:6]

Participants

Reactant 2

HCID 7043Veratrole

HCID 227378544-[(Methoxymethylamino)carbonyl]pyridine

Product 1

HCID 4285494-(2,3-Dimethoxybenzoyl)pyridine

Procedure

In Scheme H, step c, 4-[(methoxymethylamino)carbonyl]pyridine (19) is reacted with lithiated veratrole to give 4-(2,3-dimethoxybenzoyl)pyridine (12).

Sources & evidence

ORD record: ord-f48f263d54234eb08ea2e9c1750b2269
Source dataset: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06713627B2

Linked notes

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