Ethyl 3-oxohexanoate → HCID 178439449, compound

HRID 514329

Reaction equation

HRID 514329 reaction equation
[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].O=[C:12]([CH2:19][CH2:20][CH3:21])[CH2:13][C:14](OCC)=[O:15]>>[OH:15][C:14]1[N:1]([C:3]2[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=2)[N:2]=[C:12]([CH2:19][CH2:20][CH3:21])[CH:13]=1

Participants

3

Reactant 2

HCID 238498Ethyl 3-oxohexanoateHCID 201187142-Hydrazinylpyridine-4-carbonitrile

Product 1

HCID 178439449HCID 178439449, compoundYield 44%

Procedure

The title compound was prepared in 44% yield from 2-hydrazinylpyridine-4-carbonitrile (PREPARATION 2) and ethyl 3-oxohexanoate according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C12H12N4O, 229. Found, 229.

Sources & evidence

ORD record
ord-658423a5b2f54b7d80fc58c558720160
Source dataset
uspto-grants-2015_08
Patent number
US09107916B2

Linked notes

Loading…