Reaction equation
[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].[CH:11]1([C:16](=O)[CH2:17][C:18](OCC)=[O:19])[CH2:15][CH2:14][CH2:13][CH2:12]1>>[CH:11]1([C:16]2[CH:17]=[C:18]([OH:19])[N:1]([C:3]3[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=3)[N:2]=2)[CH2:15][CH2:14][CH2:13][CH2:12]1Participants
3
Procedure
The title compound was prepared in 72% yield from 2-hydrazinylpyridine-4-carbonitrile (PREPARATION 2) and ethyl 3-cyclopentyl-3-oxopropanoate according to the procedure for the preparation of Example 158, part A.
Sources & evidence
- ORD record
- ord-b44267306b0a4868a7022b6bb49cc2fe
- Source dataset
- uspto-grants-2015_08
- Patent number
- US09107916B2
Linked notes
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