2-Hydrazinylpyridine-4-carbonitrile → HCID 178510219, compound

Reaction equation

[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].[Cl:11][C:12]1[CH:13]=[C:14]([CH2:19][C:20](=O)[CH2:21][C:22](OC)=[O:23])[CH:15]=[C:16]([Cl:18])[CH:17]=1>>[Cl:11][C:12]1[CH:13]=[C:14]([CH2:19][C:20]2[CH:21]=[C:22]([OH:23])[N:1]([C:3]3[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=3)[N:2]=2)[CH:15]=[C:16]([Cl:18])[CH:17]=1

Participants

Reactant 2

HCID 201187142-Hydrazinylpyridine-4-carbonitrile

HCID 86725683Methyl 4-(3,5-dichlorophenyl)-3-oxobutanoate

Product 1

HCID 178510219HCID 178510219, compound

Procedure

The title compound was prepared from 2-hydrazinylpyridine-4-carbonitrile (PREPARATION 2) and methyl 4-(3,5-dichlorophenyl)-3-oxobutanoate according to the procedure for the preparation of Example 158, part A.

Sources & evidence

ORD record: ord-e0a7b870ca5d43409c079de8d33a8383
Source dataset: uspto-grants-2015_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09107916B2

Reaction notes

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