HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron trifluoride → 3-Allyloxymethyl-7-amino-ceph-3-eme-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron trifluoride | HCID 6356 | — |
| Reactant | Allyl Alcohol | HCID 7858 | — |
| Reactant | 7-Aminocephalosporanic acid | HCID 441328 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 3-Allyloxymethyl-7-amino-ceph-3-eme-4-carboxylic acid | HCID 131716787 | — |
Reaction Steps
Using the procedure of Step A of Example 8, 27.2 g of 7-amino-cephalosporanic acid, 170 ml of the etherate of boron trifluoride, 136 ml of allyl alcohol and 115 ml of triethylamine were reacted and the 9 g of raw product was purified successively twice with hot hydrochloric acid and ammonium hydroxide to obtain 4.72 g of 3-allyloxymethyl-7-amino-ceph-3-eme-4-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05243043 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-dcaa90fa626041689c210e2969f0e25b |
| Source note | uspto-grants-1993_09 |