HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-3-(4-chlorophenyl)propan-1-ol → 4-(4-Chlorophenyl)-N-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)-5,6-dihydro-4H-1,3-oxazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-3-(4-chlorophenyl)propan-1-ol | HCID 17039435 | — |
| Reactant | 3-(4-Isothiocyanatophenyl)-1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazole | HCID 118590165 | — |
| Product | 4-(4-Chlorophenyl)-N-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)-5,6-dihydro-4H-1,3-oxazin-2-amine | HCID 118590154 | — |
Reaction Steps
The title compound was prepared with 3-amino-3-(4-chlorophenyl)propan-1-ol and 3-(4-isothiocyanato-phenyl)-1-(4-trifluoromethoxy-phenyl)-1H-1,2,4-triazole and isolated as an off-white solid (0.150 g, 64%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09326516B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-68f43543ba9b4ec38d734d024f459c2d |
| Source note | uspto-grants-2016_05 |