HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinamine → 6,7-Dihydroxy-4-(3'-chloroanilino)quinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinamine | HCID 2051 | — |
| Reactant | Sodium ethanethiolate | HCID 4459711 | — |
| Product | 6,7-Dihydroxy-4-(3'-chloroanilino)quinazoline | HCID 135682000 | 68% |
Reaction Steps
Using an analogous procedure to that described in Example 4, 6,7-dimethoxy-4-(3'-chloroanilino)quinazoline was reacted with sodium ethanethiolate to give 6,7-dihydroxy-4-(3'-chloroanilino)quinazoline in 68% yield, m.p. 233°-235° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05616582 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-ea8bfac9caf943ed86da84b26f5329af |
| Source note | uspto-grants-1997_04 |