HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formamide → 6-Nitro-3,4-dihydroquinazolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | 2-Amino-5-nitrobenzoic acid | HCID 12032 | — |
| Product | 6-Nitro-3,4-dihydroquinazolin-4-one | HCID 135398502 | 82% |
Reaction Steps
Using an analogous procedure to that described in the first paragraph of the portion of Example 1 which is concerned with the preparation of starting materials, 5-nitroanthranilic acid was reacted with formamide to give 6-nitroquinazolin-4-one in 82% yield, m.p. 268°-271° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05616582 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-66692aa56892493bab2bcf912181f8a8 |
| Source note | uspto-grants-1997_04 |