HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Thiazolecarboxylic acid → N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]thiazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Thiazolecarboxylic acid | HCID 304271 | — |
| Reactant | 2-Buten-1-amine, 4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-, (Z)- | HCID 13672473 | — |
| Product | N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]thiazole-4-carboxamide | HCID 67725963 | 68% |
Reaction Steps
Following a procedure similar to that described in Example 13, but using 4-(4-piperidinomethyl-2-pyridyloxy) -cis-2-butenylamine and 4-thiazolecarboxylic acid as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as an oil in a 68% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05616579 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-5cfa5dff5781453181f01f9c06a67116 |
| Source note | uspto-grants-1997_04 |