HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.8.0
  1. Home
  2. /Reaction

1-Benzofuran-2-sulfonyl chloride → HCID 67972570, compound

HRID 520888
Notes
Print preview

Reaction equation

HRID 520888 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH2:10][C:11]2[CH:16]=[CH:15][C:14]([N+:17]([O-:19])=[O:18])=[CH:13][CH:12]=2)=[C:6]([CH:8]=1)[NH2:7].[O:20]1[C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=2[CH:22]=[C:21]1[S:29](Cl)(=[O:31])=[O:30]>N1C=CC=CC=1>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH2:10][C:11]2[CH:16]=[CH:15][C:14]([N+:17]([O-:19])=[O:18])=[CH:13][CH:12]=2)=[C:6]([NH:7][S:29]([C:21]2[O:20][C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=3[CH:22]=2)(=[O:30])=[O:31])[CH:8]=1
ParticipantsProcedureSources & evidenceReaction notes

Participants

4

Reactant 2

HCID 27951721-Benzofuran-2-sulfonyl chlorideHCID 126182135-Chloro-2-((4-nitrobenzyl)thio)aniline

Product 1

HCID 67972570HCID 67972570, compoundYield 72%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Following General Procedure B, the title compound (475 mg, 72%) was prepared from 5-chloro-2-((4-nitrobenzyl)thio)aniline (411 mg, 1.40 mmol) and benzofuran-2-sulfonyl chloride (303 mg, 1.40 mmol) in pyridine (5 ml).

Sources & evidence

ORD record
ord-3b844f9c5316432f952afbc222b9da42
Source dataset
uspto-grants-2016_05
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US09328067B2

Reaction notes

Loading…

On this pageParticipantsProcedureSources & evidenceReaction notes