Heptanoic Acid → 2-Propylheptanoic acid

HRID 522252

Reaction equation

HRID 522252 reaction equation
[OH-].[Na+].[C:3]([OH:11])(=[O:10])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].[CH2:12]([CH:15](CCCCC)C=O)[CH2:13]C>O>[CH2:13]([CH:4]([CH2:5][CH2:6][CH2:7][CH2:8][CH3:9])[C:3]([OH:11])=[O:10])[CH2:12][CH3:15]

Participants

5

Reactant 3

HCID 8094Heptanoic AcidHCID 14798Sodium HydroxideHCID 30186342-Propylheptanal

Product 1

HCID 357282-Propylheptanoic acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A reactor was charged with 0.2 g (0.005 mol) of sodium hydroxide (manufactured by Kanto Chemical Co., Inc.), 1 g of water, and 0.8 g (0.006 mol) of heptanoic acid (manufactured by Kishida Chemical Co., Ltd.), and the mixture was stirred. After the addition of 47 g of 2-propylheptanal, the mixture was bubbled with air at 40° C. for 15 hours. The mixture was stirred at 130° C. for 4 hours with nitrogen bubbling to obtain crude 2-propylheptanoic acid.

Workup

  1. customthe mixture was bubbled with air at 40° C. for 15 hours
  2. stirringThe mixture was stirred at 130° C. for 4 hours with nitrogen bubbling

Sources & evidence

ORD record
ord-60a94c02c1db45ad99ce7e0235de28e4
Source dataset
uspto-grants-2016_05
Patent number
US09328306B2

Linked notes

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