Methyl isobutyrate → Methyl 3-[3-(benzyloxy)-4-methoxyphenyl]-2,2-dimethyl-3-oxopropanoate
Reaction equation
[CH3:1][CH:2]([CH3:7])[C:3]([O:5][CH3:6])=[O:4].[CH2:8]([O:15][C:16]1[CH:17]=[C:18]([CH:22]=[CH:23][C:24]=1[O:25][CH3:26])[C:19](Cl)=[O:20])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[CH2:8]([O:15][C:16]1[CH:17]=[C:18]([C:19](=[O:20])[C:2]([CH3:7])([CH3:1])[C:3]([O:5][CH3:6])=[O:4])[CH:22]=[CH:23][C:24]=1[O:25][CH3:26])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1Participants
3
Procedure
Prepared analogously as described for the example D1 using methyl 2-methylproponate and 3-benzyloxy-4-methoxybenzoyl chloride as starting compounds.
Workup
- customPrepared analogously
Sources & evidence
- ORD record
- ord-5829f834b5584cee850e156d946d2bc2
- Source dataset
- uspto-grants-2016_05
- Patent number
- US09340522B2
Reaction notes
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