Ethyl 2,4-dioxovalerate → 1-[6-(4-Chloro-phenylamino)-9-methyl-9h-purin-2-yl]-5-methyl-1h-pyrazole-3-carboxylic acid ethyl ester

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]2[N:17]=[C:16]([NH:18][NH2:19])[N:15]=[C:14]3[C:10]=2[N:11]=[CH:12][N:13]3[CH3:20])=[CH:4][CH:3]=1.[CH3:21][CH2:22][O:23][C:24]([C:26]([CH2:28][C:29]([CH3:31])=O)=O)=[O:25]>>[CH2:22]([O:23][C:24]([C:26]1[CH:28]=[C:29]([CH3:31])[N:18]([C:16]2[N:15]=[C:14]3[C:10]([N:11]=[CH:12][N:13]3[CH3:20])=[C:9]([NH:8][C:5]3[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=3)[N:17]=2)[N:19]=1)=[O:25])[CH3:21]