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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 52604Generated: October 25, 2026

Dimethylhydantoin → 4-[(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]benzonitrile

https://huagongshe.com/reaction/52604

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylhydantoinHCID 6491—
Reactant4-(Bromomethyl)benzonitrileHCID 86996—
ReactantPotassium tertbutoxideHCID 50987170—
Product4-[(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]benzonitrileHCID 1897593498%

Reaction Steps

Prepared analogously to Example 92a) from 5,5-dimethylhydantoin and 4-(bromomethyl)-benzonitrile in the presence of potassium-tert.-butoxide in a yield of 98% of theory.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05616620
Source datasetuspto-grants-1997_04
ORD IDord-705a6d6bf783472898ca9a71cec7e30d
Source noteuspto-grants-1997_04