4-(Isopropylthio)benzylamine → 2-(4-(N-cyano-S-isopropylsulfinimidoyl)benzyl)isoindoline-1,3-dione
Reaction equation
[C:1]([N:3]=[S:4]([C:7]1[CH:24]=[CH:23][C:10]([CH2:11][N:12]2[C:20](=[O:21])[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[C:13]2=[O:22])=[CH:9][CH:8]=1)[CH2:5][CH3:6])#[N:2].[CH:25](SC1C=CC(CN)=CC=1)(C)C>>[C:1]([N:3]=[S:4]([C:7]1[CH:24]=[CH:23][C:10]([CH2:11][N:12]2[C:20](=[O:21])[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[C:13]2=[O:22])=[CH:9][CH:8]=1)[CH:5]([CH3:25])[CH3:6])#[N:2]Participants
3
Procedure
The title compound is prepared in analogy to preparation 13a, substituting 4-(ethylthio)-benzylamine with 4-(isopropylthio)benzylamine ESI mass spectrum: [M+H]+=352; r.t. HPLC: 0.50 min (X012_S01).
Workup
- customr.t
- custom0.50 min (X012_S01)