1-Phenethylamine, (-)- → 1-Phenethylamine, (-)-

HRID 52791

Reaction equation

HRID 52791 reaction equation
[C:1]([CH2:4][CH:5]([CH2:10][CH:11]([CH3:13])[CH3:12])[CH2:6][C:7]([OH:9])=[O:8])(=[O:3])[NH2:2].[C:14]1([C@@H:20]([NH2:22])[CH3:21])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[C:14]1([C@@H:20]([NH2:22])[CH3:21])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[C:1]([CH2:4][C@H:5]([CH2:10][CH:11]([CH3:13])[CH3:12])[CH2:6][C:7]([OH:9])=[O:8])(=[O:3])[NH2:2]

Participants

4

Reactant 2

HCID 758181-Phenethylamine, (-)-HCID 108670833-(Carbamoylmethyl)-5-methylhexanoic acid

Product 2

HCID 758181-Phenethylamine, (-)-HCID 22871591(3S)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid

Procedure

Combining (±)-3-(carbamoylmethyl)-5-methylhexanoic acid with (S)-(-)-α-phenylethylamine in a solution to obtain the (S)-(-)-α-phenylethylamine salt of (S)-(+)-3-(carbamoylmethyl)-5-methylhexanoic acid, which crystallizes out of the solution;

Sources & evidence

ORD record
ord-4e4694c3e4b3494fa0872831e08c4df8
Source dataset
uspto-grants-1997_04
Patent number
US05616793

Linked notes

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