4-(2-Bromo-4-(Trifluoromethyl)Phenyl)-3,4-Dihydro-2H-Benzo[B][1,4]Oxazine-7-Sulfonyl Chloride → perfluorophenyl 4-(2-bromo-4-(trifluoromethyl)phenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonate

HRID 528545

Reaction equation

HRID 528545 reaction equation
[Br:1]C1C=C(C(F)(F)F)C=CC=1N1CCOC2C=C(S(Cl)(=O)=O)C=CC1=2.Cl[C:27]1[CH:32]=[C:31]([C:33]([F:36])([F:35])[F:34])[CH:30]=[CH:29][C:28]=1[N:37]1[CH2:42][CH2:41][O:40][C:39]2[CH:43]=[C:44]([S:47]([O:50][C:51]3[C:56]([F:57])=[C:55]([F:58])[C:54]([F:59])=[C:53]([F:60])[C:52]=3[F:61])(=[O:49])=[O:48])[CH:45]=[CH:46][C:38]1=2>>[Br:1][C:27]1[CH:32]=[C:31]([C:33]([F:36])([F:35])[F:34])[CH:30]=[CH:29][C:28]=1[N:37]1[CH2:42][CH2:41][O:40][C:39]2[CH:43]=[C:44]([S:47]([O:50][C:51]3[C:56]([F:57])=[C:55]([F:58])[C:54]([F:59])=[C:53]([F:60])[C:52]=3[F:61])(=[O:49])=[O:48])[CH:45]=[CH:46][C:38]1=2

Participants

3

Reactant 2

HCID 897618504-(2-Bromo-4-(Trifluoromethyl)Phenyl)-3,4-Dihydro-2H-Benzo[B][1,4]Oxazine-7-Sulfonyl ChlorideHCID 89761892perfluorophenyl 4-(2-chloro-4-(trifluoromethyl)phenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonate

Product 1

HCID 89761935perfluorophenyl 4-(2-bromo-4-(trifluoromethyl)phenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonate

Procedure

Perfluorophenyl 4-(2-bromo-4-(trifluoromethyl)phenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonate was prepared from INTERMEDIATE C according to the procedure used to prepare INTERMEDIATE F. MS (ESI, positive) m/z: 625.8 (M+Na).

Sources & evidence

ORD record
ord-af89dbf0860848f69e2dc1d0c8ac38ea
Source dataset
uspto-grants-2016_05
Patent number
US09346798B2

Linked notes

Loading…