HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 3,4,5-Triacetoxybenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | Benzoic acid, 3,4,5-tris(acetyloxy)- | HCID 95088 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3,4,5-Triacetoxybenzoyl chloride | HCID 155506 | — |
Reaction Steps
3,4,5-Triacetoxybenzoic acid (296.23 g, 1 mol) was slurried in a 2 L flask in CH2Cl2 (1.0 L), and oxalyl chloride (113 mL, 1.3 mol) as added, followed by slow, dropwise addition of N,N-dimethylformamide (1.5 mL). After 2 hours at RT, gas evolution had ceased, and 3,4,5-triacetoxybenzoyl chloride was isolated by evaporation under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05244763 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-6fca121f54ad4dbeb09f154726606a7f |
| Source note | uspto-grants-1993_09 |