Chloro(diphenyl)silane → Benzyl 5-(chlorodiphenylsilyl)pentanoate

HRID 530135

Reaction equation

HRID 530135 reaction equation
[Cl:1][SiH:2]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[C:15]([O:21][CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)(=[O:20])[CH2:16][CH2:17][CH:18]=[CH2:19]>>[Cl:1][Si:2]([C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)[CH2:19][CH2:18][CH2:17][CH2:16][C:15]([O:21][CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)=[O:20]

Participants

3

Reactant 2

HCID 74206Chloro(diphenyl)silaneHCID 100520354-Pentenoic acid, phenylmethyl ester

Product 1

HCID 90418864Benzyl 5-(chlorodiphenylsilyl)pentanoate

Conditions

Temperature
60 °C

Procedure

To a mixture of chlorodiphenylsilane (0.49 g; 2.58 mmol) and benzyl pent-4-enoate (0.50 g; 2.58 mmol) under argon was added two drops of Karstedt's catalyst solution (in xylenes; ˜2% Pt). The reaction vessel was sealed and the mixture was heated to 60° C. for 15 hours. The crude liquid was used without purification.

Workup

  1. customThe reaction vessel was sealed
  2. customThe crude liquid was used without purification

Sources & evidence

ORD record
ord-6cd526816cce4681ae3f154cca16a097
Source dataset
uspto-grants-2016_05
Patent number
US09352049B2

Linked notes

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