2-(Diethylamino)ethanethiol → 1,1-Dicyclohexyl-3-[5-(2-diethylamino-ethylsulfanyl)-thiazol-2-yl]-urea

HRID 532015

Reaction equation

HRID 532015 reaction equation
[CH:1]1([N:7]([CH:19]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)[C:8]([NH:10][C:11]2[S:12][C:13]([S:16]C#N)=[CH:14][N:15]=2)=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.SC[C@@H]([C@@H](CS)O)O.[CH2:33]([N:35]([CH2:39][CH3:40])[CH2:36][CH2:37]S)[CH3:34]>>[CH:1]1([N:7]([CH:19]2[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]2)[C:8]([NH:10][C:11]2[S:12][C:13]([S:16][CH2:34][CH2:33][N:35]([CH2:39][CH3:40])[CH2:36][CH3:37])=[CH:14][N:15]=2)=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 160322-(Diethylamino)ethanethiolHCID 439352DithioerythritolHCID 866111921,1-Dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea

Product 1

HCID 578838961,1-Dicyclohexyl-3-[5-(2-diethylamino-ethylsulfanyl)-thiazol-2-yl]-urea

Procedure

Prepared as described in general procedure (H) using 1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea, dithioerythritol and 2-diethylamino-ethanethiol

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-4cca5df466b24c84bf2859a1a1603d1f
Source dataset
uspto-grants-2014_10
Patent number
USRE045183E1

Linked notes

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