Dimethylsulphamoyl chloride → HCID 178486167, compound

HRID 532047

Reaction equation

[Cl:1][C:2]1[S:6][C:5]([NH:7][C:8](=[O:23])[N:9]([C@H:16]2[CH2:21][CH2:20][C@H:19]([CH3:22])[CH2:18][CH2:17]2)[CH:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)=[N:4][CH:3]=1.[CH3:24][N:25]([CH3:30])[S:26](Cl)(=[O:28])=[O:27]>>[CH3:24][N:25]([CH3:30])[S:26]([N:13]1[CH2:12][CH2:11][CH:10]([N:9]([C@H:16]2[CH2:21][CH2:20][C@H:19]([CH3:22])[CH2:18][CH2:17]2)[C:8]([NH:7][C:5]2[S:6][C:2]([Cl:1])=[CH:3][N:4]=2)=[O:23])[CH2:15][CH2:14]1)(=[O:28])=[O:27]

Participants

Reactant 2

HCID 83372Dimethylsulphamoyl chloride

HCID 178461370HCID 178461370, compound

Product 1

HCID 178486167HCID 178486167, compound

Procedure

Prepared in a similar manner to Example 554 using 3-(5-chloro-thiazol-2-yl)-1-(trans-4-methyl-cyclohexyl)-1-piperidin-4-yl-urea and dimethylsulfamoyl chloride

Sources & evidence

ORD record: ord-de56b59350b5429da9becc30f2a868ee
Source dataset: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: USRE045183E1

Linked notes

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