HuagongsheHuagongshe Chemistry Print Report · For research reference only
trans-Crotonyl chloride → (R,E)-3-but-2-enoyl-4-phenyloxazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | trans-Crotonyl chloride | HCID 643131 | — |
| Reactant | (4R)-4-phenyl-1,3-oxazolidin-2-one | HCID 730425 | — |
| Product | (R,E)-3-but-2-enoyl-4-phenyloxazolidin-2-one | HCID 10242987 | 81.1% |
Reaction Steps
trans-Crotonoyl chloride (2.67 g, 10.24 mmol, Aldrich) was coupled with (R)-4-phenyl-2-oxazolidinone (1.46 g, 8.9 mmol) according to the procedure of Example 1c to afford the title compound (1.67 g). MS m/z 232 (M+H)+, 249 (M+NH4)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05618949 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-2b7ae0440cbb449b91c594c90e18c87f |
| Source note | uspto-grants-1997_04 |