Formaldehyde → 2-Ethylhexanal

HRID 53410

Reaction equation

HRID 53410 reaction equation
[CH2:1]([CH:3]([CH2:6][CH2:7][CH2:8][CH3:9])[CH:4]=[O:5])[CH3:2].[CH2:10]=[O:11]>>[CH2:1]([C:3]([CH2:10][OH:11])([CH2:6][CH2:7][CH2:8][CH3:9])[CH:4]=[O:5])[CH3:2].[CH2:1]([CH:3]([CH2:6][CH2:7][CH2:8][CH3:9])[CH:4]=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 312412-Ethylhexanal

Product 2

HCID 312412-EthylhexanalHCID 125384672-Ethyl 2-(hydroxymethyl)hexanal

Procedure

In U.S. Pat. No. 5,146,004, 2-ethyl-2-(hydroxymethyl) hexanal is prepared from 2-ethyl hexanal, formaldehyde and a tertiary amine. Any unreacted 2-ethyl hexanal can be isolated by azeotropic distillation of the organic phase of the raw product, and 2-butyl-2-ethyl-1,3 propane diol is obtained from the purified organic phase of the raw product by catalytic hydrogenation, with a yield of 85-88%. The hydrogenation is carried out by using a nickel catalyst.

Sources & evidence

ORD record
ord-6beb40bbe11e48faa80d761d12ed108c
Source dataset
uspto-grants-1997_04
Patent number
US05618985

Linked notes

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