N-Benzylformamide → N-benzyl formamide NaSCN

HRID 535215

Reaction equation

[CH2:1]([NH:8][CH:9]=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S-:11][C:12]#[N:13].[Na+:14]>>[CH2:1]([NH:8][CH:9]=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S-:11][C:12]#[N:13].[Na+:14]

Participants

Reactant 2

HCID 80654N-Benzylformamide

HCID 516871Sodium thiocyanate

Product 1

HCID 131731936N-benzyl formamide NaSCNYield 100.3%

Conditions

Temperature: 30 °C

Procedure

To a round-bottom flask, 9.9 g of purified N-benzyl formamide and 4 g of NaSCN (sodium thiocyanate) were introduced. The mixture was agitated gradually under nitrogen atmosphere at 30° C. for 40 minutes, and then at room temperature for 5 hours to obtain 10.7 g of N-benzyl formamide-NaSCN eutectic mixture.

Sources & evidence

ORD record: ord-92c554d1877b4115a46c924621464c74
Source dataset: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08858837B2

Linked notes

Loading…