Sulfuric Acid → 2-[Ethyl(phenyl)amino]ethyl hydrogen sulfate

HRID 537630

Reaction equation

HRID 537630 reaction equation
[CH2:1]([N:3]([CH2:10][CH2:11][OH:12])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[CH3:2].[S:13](=O)(=[O:16])([OH:15])[OH:14]>O>[S:13]([OH:16])([O:12][CH2:11][CH2:10][N:3]([CH2:1][CH3:2])[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1)(=[O:15])=[O:14]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 623382-(N-ethylanilino)ethanol

Product 1

HCID 235697472-[Ethyl(phenyl)amino]ethyl hydrogen sulfate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

In 1.1, 16.5 grams (g) (0.10 mol) of 2-(N-ethylanilino)ethanol were added to 25.0 milliliters (ml) of concentrated sulfuric acid at a temperature of 35 to 40 degrees Celsius (° C.). The reaction proceeded slightly exothermically and was held within the specified temperature range by cooling with iced water. The mixture was stirred for an additional 2 hours. On completion of the reaction, the mixture was poured onto ice and made up to 250 ml by adding water. The result was a transparent yellow solution, which was used in the next stage with no further processing.

Workup

  1. customOn completion of the reaction
  2. additionthe mixture was poured onto ice

Sources & evidence

ORD record
ord-fc24090ca5e74691b412e37e0af60a8b
Source dataset
uspto-grants-2014_10
Patent number
US08864849B1

Linked notes

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