Phenylalanine amide → (S)-2-(2,3-Dioxo-2,3-dihydro-1H-indole-5-sulfonylamino)-3-phenyl-propionamide

HRID 539502

Reaction equation

HRID 539502 reaction equation
[NH2:1][C@H:2]([C:10]([NH2:12])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.C(N[S:17]([C:20]1[CH:21]=[C:22]2[C:26](=[CH:27][CH:28]=1)[NH:25][C:24](=[O:29])[C:23]2=[O:30])(=[O:19])=[O:18])CC>>[O:29]=[C:24]1[C:23](=[O:30])[C:22]2[C:26](=[CH:27][CH:28]=[C:20]([S:17]([NH:1][C@@H:2]([CH2:3][C:4]3[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=3)[C:10]([NH2:12])=[O:11])(=[O:19])=[O:18])[CH:21]=2)[NH:25]1

Participants

3

Reactant 2

HCID 445694Phenylalanine amideHCID 112771782,3-Dioxo-2,3-dihydro-1H-indole-5-sulfonic acid propylamide

Product 1

HCID 11303301(S)-2-(2,3-Dioxo-2,3-dihydro-1H-indole-5-sulfonylamino)-3-phenyl-propionamide

Procedure

The title compound was prepared from L-Phe-NH2 following the procedure for 2,3-Dioxo-2,3-dihydro-1H-indole-5-sulfonic acid propylamide.

Sources & evidence

ORD record
ord-809a4a777c8b48e98f4b477f63d6aa32
Source dataset
uspto-grants-2014_10
Patent number
US08871718B2

Linked notes

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