Ethyl isocyanate → HCID 136197293, compound

Reaction equation

[OH:1][C:2]1[CH:3]=[CH:4][C:5]([O:19][CH2:20][CH2:21][CH3:22])=[C:6]([C:8]2[NH:13][C:12](=[O:14])[C:11]([CH2:15][CH3:16])=[C:10]([CH2:17][CH3:18])[N:9]=2)[CH:7]=1.[CH2:23]([N:25]=[C:26]=[O:27])[CH3:24]>>[CH2:23]([NH:25][C:26]([O:1][C:2]1[CH:3]=[CH:4][C:5]([O:19][CH2:20][CH2:21][CH3:22])=[C:6]([C:8]2[NH:13][C:12](=[O:14])[C:11]([CH2:15][CH3:16])=[C:10]([CH2:17][CH3:18])[N:9]=2)[CH:7]=1)=[O:27])[CH3:24]

Participants

Reactant 2

HCID 8022Ethyl isocyanate

HCID 136197392HCID 136197392, compound

Product 1

HCID 136197293HCID 136197293, compound

Procedure

The title compound was prepared by reacting the compound of example 81 with ethyl isocyanate in the same manner as that of example 35. 1H NMR (CDCl3) δ: 8.20 (1H, d), 7.25 (1H, dd), 6.99 (1H, d), 5.06 (1H, br), 4.14 (2H, t), 3.32 (2H, m), 2.66 (2H, q), 2.58 (2H, q), 1.98 (2H, m), 1.28 (3H, t), 1.22 (3H, t), 1.14 (3H, t), 1.13 (3H, t).

Sources & evidence

ORD record: ord-69fcb36af676496f842ac6562cae76a9
Source dataset: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08871777B2

Reaction notes

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