Reaction equation
C1(C2[C:13]([C:14]3[NH:18][C:17](C)=[N:16][N:15]=3)=[CH:12]C(C(O)=O)=C(C)C=2)CCC1.[F:21][C:22]1[CH:30]=[CH:29][C:25]([C:26]([OH:28])=[O:27])=[C:24]([CH3:31])[CH:23]=1.C(NN)(=O)CC>>[CH2:13]([C:14]1[NH:18][C:17]([C:30]2[C:22]([F:21])=[CH:23][C:24]([CH3:31])=[C:25]([CH:29]=2)[C:26]([OH:28])=[O:27])=[N:16][N:15]=1)[CH3:12]Participants
4
Procedure
The title compound was synthesized using standard chemical manipulations and procedures similar to those used for the preparation of compound 152.8 using 4-fluoro-2-methylbenzoic acid instead of 4-bromo-2-methylbenzoic acid and propionohydrazide instead of acetohydrazide.
Sources & evidence
- ORD record
- ord-d24fa306136c482d88a70aa8c655696d
- Source dataset
- uspto-grants-2014_10
- Patent number
- US08871790B2
Linked notes
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