Water → HCID 178443601, compound

HRID 543663Notes

Reaction equation

HRID 543663 reaction equation
[CH2:1]([NH:9][C:10]1[N:15]=[C:14]([OH:16])[C:13]([C:17]([O:19]CC)=[O:18])=[CH:12][N:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].O.[OH-].[Na+]>C(O)C>[CH2:1]([NH:9][C:10]1[N:15]=[C:14]([OH:16])[C:13]([C:17]([OH:19])=[O:18])=[CH:12][N:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

5

Reactant 3

HCID 962WaterHCID 14798Sodium HydroxideHCID 178443600HCID 178443600, compound

Product 1

HCID 178443601HCID 178443601, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-n-Octylamino-5-ethoxycarbonyl-4-hydroxypyrimidine (400 mg, 1.4 mmol) was hydrolysed in boiling water (10 ml): ethanol (3 ml) with NaOH (5 mmol, 200 mg).

Sources & evidence

ORD record
ord-9c79c000454d4027a9d4712d11f97f87
Source dataset
uspto-grants-1984_05
Patent number
US04447422

Reaction notes

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