HCID 15580707, compound → HCID 15580720, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[CH2:13][CH2:12][C:11]([NH:14][C:15](=[O:20])C(F)(F)F)=[N:10]2)[CH:5]=[CH:6][C:7]=1[Cl:8].ClC1C=C(N2CC(C)C(NC=O)=N2)C=CC=1Cl>C(O)=O>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[CH2:13][CH2:12][C:11]([NH:14][CH:15]=[O:20])=[N:10]2)[CH:5]=[CH:6][C:7]=1[Cl:8]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 5.0 g. of 3-amino-1-(3,4-dichlorophenyl)-2-pyrazoline (prepared in Example 1) and 25 ml. of a mixture of formic acid and acetic anhydride (Example 15) is allowed to stand at room temperature for one hour. The resulting solid is collected by filtration and washed with hexane. The solid is dissolved in dichloromethane and is columnized and recrystallized as described in Example 5 to give 3.85 g. of the desired product as yellow prisms, m.p. 151°-153° C.