Ammonia → 2-Amino-6-nitrobenzothiazole

HRID 543886

Reaction equation

HRID 543886 reaction equation
Cl[C:2]1[S:3][C:4]2[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:5]=2[N:6]=1.[NH3:14]>>[NH2:14][C:2]1[S:3][C:4]2[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:5]=2[N:6]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 754762-Chloro-6-nitrobenzothiazole

Product 1

HCID 227042-Amino-6-nitrobenzothiazole

Procedure

Various processes for the preparation of 2-amino-6-nitrobenzothiazole are known. For example Pubbl. ist. chim. univ. Bologna No. 2, 3-10 (1943); Chemical Abstracts 41:754 discloses the chlorination of 2-mercaptobenzothiazole to give 2-chlorobenzothiazole which is then treated with nitric and sulfuric acids to give 2-chloro-6-nitrobenzothiazole. The 2-chloro-6-nitrobenzothiazole is then treated with alcoholic ammonia under pressure at 140° to give 2-amino-6-nitrobenzothiazole. No yields are stated in the English abstract.

Sources & evidence

ORD record
ord-7e23221a85904d2c96a13ae0023a2fbc
Source dataset
uspto-grants-1984_05
Patent number
US04447617

Linked notes

Loading…