Ammonia → 2-Amino-6-nitrobenzothiazole
Reaction equation
S[C:2]1[S:3][C:4]2[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:5]=2[N:6]=1.[NH3:14]>>[NH2:14][C:2]1[S:3][C:4]2[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:5]=2[N:6]=1Participants
3
Procedure
It has also been reported [see J. Amer. Chem. Soc. 49, 1748 (1927)] that treatment of 2-mercapto-6-nitrobenzothiazole with concentrated aqueous ammonia under pressure at 160° C. followed by crystallization from alcohol and treatment with bone black gives 2-amino-6-nitrobenzothiazole in small yield.
Workup
- customat 160° C.
- customfollowed by crystallization from alcohol and treatment with bone black
Sources & evidence
- ORD record
- ord-9fbb161e393d42a4bb1b6d10c358f805
- Source dataset
- uspto-grants-1984_05
- Patent number
- US04447617
Reaction notes
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