Cyclobutane-1,3-dione → 2-[[2-[4-(4-Trifluoromethylphenoxy)phenoxy]propionyl]]cyclobutane-1,3-dione

HRID 544192Notes

Reaction equation

HRID 544192 reaction equation
[F:1][C:2]([F:23])([F:22])[C:3]1[CH:21]=[CH:20][C:6]([O:7][C:8]2[CH:19]=[CH:18][C:11]([O:12][CH:13]([CH3:17])[C:14](F)=[O:15])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1.[Tl].[C:25]1(=[O:30])[CH2:28][C:27](=[O:29])[CH2:26]1>>[F:1][C:2]([F:23])([F:22])[C:3]1[CH:21]=[CH:20][C:6]([O:7][C:8]2[CH:19]=[CH:18][C:11]([O:12][CH:13]([CH3:17])[C:14]([CH:26]3[C:27](=[O:29])[CH2:28][C:25]3=[O:30])=[O:15])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 27357Cyclobutane-1,3-dioneHCID 5359464ThalliumHCID 539414602-{4-[4-(Trifluoromethyl)phenoxy]phenoxy}propanoyl fluoride

Product 1

HCID 204271862-[[2-[4-(4-Trifluoromethylphenoxy)phenoxy]propionyl]]cyclobutane-1,3-dione

Procedure

In the same manner, 2-[4-(4-trifluoromethylphenoxy)phenoxy]propionic acid fluoride is reacted with the thallium salt of cyclobutane-1,3-dione to yield 2-[[2-[4-(4-trifluoromethylphenoxy)phenoxy]propionyl]]cyclobutane-1,3-dione (V; Y is H, Z is CF3, R1 is CH3 and n is zero).

Sources & evidence

ORD record
ord-1d6ec8641aee45d7a517e581ba91c78a
Source dataset
uspto-grants-1984_05
Patent number
US04448965

Reaction notes

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