HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → N-[[(4-Nitrophenyl)methoxy]carbonyl]-L-isoleucine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | L-Isoleucine | HCID 6306 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Carbonic acid 4-Nitrophenyl (4-Nitrophenyl)methyl Ester | HCID 21829967 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-[[(4-Nitrophenyl)methoxy]carbonyl]-L-isoleucine | HCID 12184447 | 24.5% |
Reaction Steps
The title compound is prepared by the procedure of Example 255 using 14.73 g of product from Example 254, 6.07 g of L-isoleucine, 12.73 ml of triethylamine and 556 ml of 4:1 ethyl alcohol:water to give 3.52 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05623081 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-1849cdd34ca7460f86457d497ba7c0d0 |
| Source note | uspto-grants-1997_04 |