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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 548403Generated: October 23, 2026

2-Thiopheneglyoxylic acid → 2-Oxo-3-thiophen-2-yl-1,2-dihydro-quinoxaline-6-carboxylic acid ethyl ester

https://huagongshe.com/en/reaction/548403

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneglyoxylic acidHCID 77694—
ReactantEthyl 3,4-DiaminobenzoateHCID 458855—
Product2-Oxo-3-thiophen-2-yl-1,2-dihydro-quinoxaline-6-carboxylic acid ethyl esterHCID 67207044—

Reaction Steps

The quinoxalin-2-one of the present example is prepared with 3,4-Diamino-benzoic acid ethyl ester and (thiophen-2-yl) oxo-acetic acid via the method described in Example 12 to afford 2-Oxo-3-thiophen-2-yl-1,2-dihydro-quinoxaline-6-carboxylic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE042375E1
Source datasetuspto-grants-2011_05
ORD IDord-16de8acaf7d34d47a9745002fce7317e
Source noteuspto-grants-2011_05