Cabergoline → HCID 131728839, compound
Reaction equation
[CH3:1][CH:2]([CH:4]1[NH:28][C:26](=[O:27])[CH:25]([CH2:29][CH2:30][CH2:31][CH2:32][NH2:33])[NH:24][C:22](=[O:23])[CH:21]([CH2:34][C:35]2[C:43]3[C:38](=[CH:39][CH:40]=[CH:41][CH:42]=3)[NH:37][CH:36]=2)[NH:20][C:18](=[O:19])[CH:17]([CH2:44][C:45]2[CH:50]=[CH:49][C:48]([OH:51])=[CH:47][CH:46]=2)[NH:16][C:14](=[O:15])[CH:13]([NH:52][C:53]([CH:55]([NH2:67])[CH2:56][C:57]2[CH:66]=[CH:65][C:64]3[C:59](=[CH:60][CH:61]=[CH:62][CH:63]=3)[CH:58]=2)=[O:54])[CH2:12][S:11][S:10][CH2:9][CH:8]([C:68]([NH:70][CH:71]([C:75]([NH2:77])=[O:76])[CH:72]([OH:74])[CH3:73])=[O:69])[NH:7][C:5]1=[O:6])[CH3:3].[CH3:78][CH2:79][NH:80][C:81]([N:83]([C:90]([C@H:92]1[CH2:107][N:106]([CH2:108][CH:109]=[CH2:110])[C@H:105]2[C@@H:94]([C:95]3[C:100]4[C:101]([CH2:104]2)=[CH:102][NH:103][C:99]=4[CH:98]=[CH:97][CH:96]=3)[CH2:93]1)=[O:91])[CH2:84][CH2:85][CH2:86][N:87]([CH3:89])[CH3:88])=[O:82]>O>[CH3:3][CH:2]([CH:4]1[NH:28][C:26](=[O:27])[CH:25]([CH2:29][CH2:30][CH2:31][CH2:32][NH2:33])[NH:24][C:22](=[O:23])[CH:21]([CH2:34][C:35]2[C:43]3[C:38](=[CH:39][CH:40]=[CH:41][CH:42]=3)[NH:37][CH:36]=2)[NH:20][C:18](=[O:19])[CH:17]([CH2:44][C:45]2[CH:46]=[CH:47][C:48]([OH:51])=[CH:49][CH:50]=2)[NH:16][C:14](=[O:15])[CH:13]([NH:52][C:53]([CH:55]([NH2:67])[CH2:56][C:57]2[CH:66]=[CH:65][C:64]3[C:59](=[CH:60][CH:61]=[CH:62][CH:63]=3)[CH:58]=2)=[O:54])[CH2:12][S:11][S:10][CH2:9][CH:8]([C:68]([NH:70][CH:71]([C:75]([NH2:77])=[O:76])[CH:72]([OH:74])[CH3:73])=[O:69])[NH:7][C:5]1=[O:6])[CH3:1].[CH3:78][CH2:79][NH:80][C:81]([N:83]([C:90]([C@H:92]1[CH2:107][N:106]([CH2:108][CH:109]=[CH2:110])[C@H:105]2[C@@H:94]([C:95]3[C:100]4[C:101]([CH2:104]2)=[CH:102][NH:103][C:99]=4[CH:98]=[CH:97][CH:96]=3)[CH2:93]1)=[O:91])[CH2:84][CH2:85][CH2:86][N:87]([CH3:89])[CH3:88])=[O:82]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
1.0 g. SOMATULINE and 0.1 g CABERGOLINE are added to a 5.0 ml syringe. The two powders are dry-mixed wit a spatula and put under vacuum, e.g., using a vacuum pump. The mixed powder is connected via a valve to another 5 ml syringe containing 2.6 ml water. The valve is opened and the water is mixed with powder through the valve. 10 transfers of the resultant solution are made between the two syringes via alternate depression of their respective plungers to produce a homogeneous, semi-solid mixture. The semisolid is then loaded into 0.3 ml insulin syringes at doses of 0.225 ml.