4-Bromo-1,2-dichlorobenzene → 3-(3,4-Dichlorophenyl)-9-methyl-3,9-diazaspiro[5.5]undecane

HRID 548943

Reaction equation

HRID 548943 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][C:5]2([CH2:12][CH2:11][NH:10][CH2:9][CH2:8]2)[CH2:4][CH2:3]1.Br[C:14]1[CH:19]=[CH:18][C:17]([Cl:20])=[C:16]([Cl:21])[CH:15]=1>>[Cl:21][C:16]1[CH:15]=[C:14]([N:10]2[CH2:9][CH2:8][C:5]3([CH2:4][CH2:3][N:2]([CH3:1])[CH2:7][CH2:6]3)[CH2:12][CH2:11]2)[CH:19]=[CH:18][C:17]=1[Cl:20]

Participants

3

Reactant 2

HCID 290134-Bromo-1,2-dichlorobenzeneHCID 218132933-Methyl-3,9-diazaspiro[5.5]undecane

Product 1

HCID 159406443-(3,4-Dichlorophenyl)-9-methyl-3,9-diazaspiro[5.5]undecane

Procedure

Was prepared according to method A from 3-methyl-3,9-diaza-spiro[5.5]undecane and 1-bromo-3,4-dichlorobenzene as a yellow oil. LC-ESI−HRMS of [M+H]+ shows 313.1238 Da. Calc. 313.123829 Da, dev. −0.1 ppm.

Workup

  1. customWas prepared

Sources & evidence

ORD record
ord-8adc561014414367a43e66ed6c2e86fe
Source dataset
uspto-grants-2011_05
Patent number
US07943630B2

Linked notes

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