HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-N,N-dicyclohexylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,6-Di-tert-butyl-4-mercaptophenol | HCID 70370 | — |
| Reactant | 2-Propenamide, N,N-dicyclohexyl- | HCID 10105498 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-N,N-dicyclohexylpropanamide | HCID 9826140 | — |
Reaction Steps
The title compound of Example 3 (1.9 g, 0.008 mole), 2,6-bis(1,1-dimethylethyl)-4-mercaptophenol(2 g, 0.008 mole) and triethylamine (0.5 ml) were stirred in methanol (25 ml) for about 12 hours. The solvent was removed in vacuo on a rotary evaporator, the crude material purified by chromatography on silica and recrystallized from hexane, m.p. ca. 168.5°-172° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05244899 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-83a7fad34b684fd8a233fc5ded25c4c5 |
| Source note | uspto-grants-1993_09 |