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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 550910Generated: October 26, 2026

2,5-Dimethylphenyl isocyanate → 3-{4-[3-(2,5-dimethylphenyl)ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide

https://huagongshe.com/reaction/550910

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-Dimethylphenyl isocyanateHCID 98605—
Reactant3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamideHCID 57445354—
Product3-{4-[3-(2,5-dimethylphenyl)ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamideHCID 57445302—

Reaction Steps

75.9 mg of solid white 3-{4-[3-(2,5-dimethylphenyl)ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide are prepared as described in Example 7 starting with 3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide and 2,5-dimethylphenyl isocyanate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947706B2
Source datasetuspto-grants-2011_05
ORD IDord-d4d855120b5c4ba6930bc4134e80f29a
Source noteuspto-grants-2011_05