Diethylethanolamine → 2-(N,N-diethylamino)ethyl 1-pyrrolidineacetate

HRID 5511

Reaction equation

[N:1]1([CH2:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:12]([N:14](CCO)[CH2:15][CH3:16])[CH3:13]>>[N:1]1([CH2:6][C:7]([O:9][CH2:10][CH2:11][N:14]([CH2:15][CH3:16])[CH2:12][CH3:13])=[O:8])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

Reactant 2

HCID 7497Diethylethanolamine

HCID 2109961-Pyrrolidineacetic acid, ethyl ester

Product 1

HCID 541804822-(N,N-diethylamino)ethyl 1-pyrrolidineacetate

Procedure

Using the method of Example 5, ethyl 1-pyrrolidineacetate was reacted with 2-(N,N-diethylamino)ethanol to provide 2-(N,N-diethylamino)ethyl 1-pyrrolidineacetate, b.p. 92° C. at 250 μmHg.

Sources & evidence

ORD record: ord-6a86b0c3c8d04f9588652776384b7532
Source dataset: uspto-grants-1993_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05244997

Linked notes

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