Prostaglandin E2 → PGF2beta

HRID 55567

Reaction equation

HRID 55567 reaction equation
[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][C@H:6]([OH:25])/[CH:7]=[CH:8]/[C@@H:9]1[C@@H:14]([CH2:15]/[CH:16]=[CH:17]\[CH2:18][CH2:19][CH2:20][C:21]([OH:23])=[O:22])[C:12](=[O:13])[CH2:11][C@H:10]1[OH:24].C1C=CC=CC=1.O1CCOCC1CC(O)=O>>[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][C@H:6]([OH:25])/[CH:7]=[CH:8]/[C@@H:9]1[C@@H:14]([CH2:15]/[CH:16]=[CH:17]\[CH2:18][CH2:19][CH2:20][C:21]([OH:23])=[O:22])[C@H:12]([OH:13])[CH2:11][C@H:10]1[OH:24]

Participants

3

Reactant 2

HCID 5280360Prostaglandin E2HCID 69594947Benzene dioxane-acetic acid

Product 1

HCID 5280506PGF2beta

Procedure

The 1.3-dinitroglycerol ester of prostaglandin F2β was prepared by the same procedure from the corresponding ester of prostaglandin E2 : a viscous, colorless oil, Rf 0.16 (benzene- dioxane-acetic acid, 20:10:1), mass spectrum (FAB) m/z 517 (M+H), 501 (M+H-H2O).

Sources & evidence

ORD record
ord-2d8eeb298de547bdb83407ce2c3a445f
Source dataset
uspto-grants-1997_04
Patent number
US05625083

Linked notes

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