2,4-Difluorobenzaldehyde → bis((E)-2,4-Difluorostyrylsulfonyl)methane

HRID 557097Notes

Reaction equation

HRID 557097 reaction equation
[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:3]=1[CH:4]=O.C([CH2:14][S:15]([CH2:18][S:19]([CH2:22][C:23](O)=O)(=[O:21])=[O:20])(=[O:17])=[O:16])(O)=O>C(O)(=O)C>[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:3]=1/[CH:4]=[CH:14]/[S:15]([CH2:18][S:19](/[CH:22]=[CH:23]/[C:7]1[CH:6]=[CH:3][C:2]([F:1])=[CH:9][C:8]=1[F:10])(=[O:21])=[O:20])(=[O:17])=[O:16]

Participants

4

Reactant 2

HCID 737702,4-DifluorobenzaldehydeHCID 2252641Acetic acid, 2,2'-[methylenebis(sulfonyl)]bis-

Product 1

HCID 11654673bis((E)-2,4-Difluorostyrylsulfonyl)methaneYield 75%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 2,4-difluorobenzaldehyde (2 mmol) and carboxymethane-sulfonylmethanesulfonyl-acetic acid (1 mmol) in acetic acid (10 mL) was subjected to General Procedure 1, to yield the title compound in 75% yield. m.p. 193-195° C.

Sources & evidence

ORD record
ord-298e2bf688de494baeb371806b41bf52
Source dataset
uspto-grants-2011_11
Patent number
US08058313B2

Reaction notes

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