Methyl iodide → 5-Fluoro-2,3-dimethyl-benzothiazol-3-ium iodide
Reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]2[S:9][C:8]([CH3:10])=[N:7][C:6]=2[CH:11]=1.[I:12][CH3:13]>C(O)C>[I-:12].[F:1][C:2]1[CH:3]=[CH:4][C:5]2[S:9][C:8]([CH3:10])=[N+:7]([CH3:13])[C:6]=2[CH:11]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
13.0 g (10.4 ml, 77.7 mmol) 5-Fluoro-2-methyl-benzothiazole and 22.1 g (9.47 ml, 156 mmol) iodomethane were boiled in ethanol for 7 h. The residue was filtrated. 4.00 g=17% white powder
Workup
- filtrationThe residue was filtrated
Sources & evidence
- ORD record
- ord-ca4303ac31c042c0bca4858ea5b4ad7a
- Source dataset
- uspto-grants-2011_11
- Patent number
- US08058431B2
Reaction notes
Loading…