Acetic Acid → N'-(4-Iodophenyl)acetohydrazide

HRID 559145

Reaction equation

HRID 559145 reaction equation
[I:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][NH2:9])=[CH:4][CH:3]=1.[C:10](O)(=[O:12])[CH3:11]>>[I:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][NH:9][C:10](=[O:12])[CH3:11])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 176Acetic AcidHCID 7045914-Iodophenylhydrazine

Product 1

HCID 623860N'-(4-Iodophenyl)acetohydrazide

Procedure

A mixture of 10 g of 4-iodophenylhydrazine in 80 ml of acetic acid is refluxed for 5 hours. The reaction mixture is concentrated under vacuum, the residue is taken up with water, and the precipitate formed is filter-dried and washed with a propan-2-ol/PE (50/50; v/v) mixture. 9 g of the expected compound are obtained.

Workup

  1. temperatureis refluxed for 5 hours
  2. concentrationThe reaction mixture is concentrated under vacuum
  3. customthe precipitate formed
  4. customis filter-dried
  5. washwashed with a propan-2-ol/PE (50/50; v/v) mixture

Sources & evidence

ORD record
ord-bc6017e9c2914504b8961b1c59b6217f
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Linked notes

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