HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylimidazo[2,1-b]thiazole-2-carboxylic acid → 3-Methyl-imidazo[2,1-b]thiazole-2-carboxylic acid{(1s,2s,5r)-3-[2-amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylimidazo[2,1-b]thiazole-2-carboxylic acid | HCID 56965725 | — |
| Reactant | [2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanone | HCID 86644211 | — |
| Product | 3-Methyl-imidazo[2,1-b]thiazole-2-carboxylic acid{(1s,2s,5r)-3-[2-amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide | HCID 87229795 | — |
Reaction Steps
prepared by reaction of [2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanone with 3-Methyl-imidazo[2,1-b]thiazole-2-carboxylic acid. LC-MS (basic): tR=0.73 min; [M+H]+=497.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063099B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-a7c8a2fd6b9c4c8cbab093ce6af08ad5 |
| Source note | uspto-grants-2011_11 |