Benzylamine → Benzyl(4-isopropylcyclohexyl)amine

Reaction equation

[CH:1]([CH:4]1[CH2:9][CH2:8][C:7](=O)[CH2:6][CH2:5]1)([CH3:3])[CH3:2].[CH2:11]([NH2:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH2:11]([NH:18][CH:7]1[CH2:8][CH2:9][CH:4]([CH:1]([CH3:3])[CH3:2])[CH2:5][CH2:6]1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

Reactant 2

HCID 7504Benzylamine

HCID 794884-Isopropylcyclohexanone

Product 1

HCID 58841001Benzyl(4-isopropylcyclohexyl)amine

Procedure

Using the procedure outlined in Example 1, 4-isopropylcyclohexanone and benzylamine were converted to the title compound: RT=2.52 min; m/z (ES+)=232.1 [M+H]+.

Sources & evidence

ORD record: ord-330d5e54137047ef837ad2494fc16bb3
Source dataset: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08063247B2

Reaction notes

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