Ethyl cyanoacetate → Poly(oxy-1,2-ethanediyl), alpha-[4-(2-cyano-3-ethoxy-3-oxo-1-propenyl)phenyl]-omega-hydroxy-

HRID 561893

Reaction equation

HRID 561893 reaction equation
[C:1]([CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5])#[N:2].[OH:9][CH2:10][CH2:11][O:12][C:13]1[CH:20]=[CH:19][C:16]([CH:17]=O)=[CH:15][CH:14]=1.CCCCCC>C(O)C>[C:1]([C:3](=[CH:17][C:16]1[CH:15]=[CH:14][C:13]([O:12][CH2:11][CH2:10][OH:9])=[CH:20][CH:19]=1)[C:4]([O:6][CH2:7][CH3:8])=[O:5])#[N:2]

Participants

5

Reactant 3

HCID 7764Ethyl cyanoacetateHCID 8058HexaneHCID 89178Benzaldehyde, 4-(2-hydroxyethoxy)-

Product 1

HCID 50742116Poly(oxy-1,2-ethanediyl), alpha-[4-(2-cyano-3-ethoxy-3-oxo-1-propenyl)phenyl]-omega-hydroxy-

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ethyl cyanoacetate (1.1 eq.) and 4-(2-hydroxyethoxy)benzaldehyde (1 eq.) were combined in ethanol (1.2 M). The reaction mixture was stirred at RT for 48. To this was then added an equal volume of hexane and the title compound was isolated by filtration as a pale yellow solid.

Sources & evidence

ORD record
ord-1040e73697ea45ebbefdd1e7f8935a97
Source dataset
uspto-grants-2011_11
Patent number
US08063105B2

Linked notes

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